Education and Career Forum

i want solved paper of niper entrance exams and also the course of that exam

my dear friend
for getting solved papers and syllabus you can visit the below link:


http://niper.nic.in/

good luck...

Well entrance consists of 200 questions in 2 hours. (Please check it in Brochure). Well questions will be very easy so no need to go in depth of the topic. Basic concepts based questions are asked. M. Pharma branches and M.B.A. has a common entrance paper. So read some general knowledge aspects also…………….
This syllabus is just like GATE entrance but more specific in Basic Chemistry instead of medicinal chemistry.
Specialization subjects: What to study?
Medicinal chemistry and Bulk Drugs (Pharmaceutical Technology)
IUPAC nomenclature, R and S nomenclature, E and Z isomerism, atropiisomerism, Conformations
Hybridization, aromaticity, Huckel’s rule reaction mechanisms- Electrophilic, Nucleophilic, SN1, SN2, SNi, Elimination E1 E2 etc.
Ester hydrolysis, Aac1 Aac2……all eight mechanisms (Jerry march) Markovnikoves rule, Bredts rule, Stereoselectivity, stereospecificity, regioselectivity, chemoselectivity, chirality, stereochemistry, conformations, rearrangements, acids and bases.
Imine-enamine Tautomerism, keto-enol tautomerism, pericyclic reactions, racemic mixture, resolution methods.
Amino acids proteins, various methods for amino acid detection, Ninhydrin test, peptide sequencing, structures of amino acids, essential and nonessential amino acids,
Introduction to thermal methods of analysis like, TGA, DSC, DTA etc.
Carbohydrates classification, osazone test, mutarotation, etc,
Various Heterocycles, Heterocycle synthesis, reactions.
Introduction to Redox reactions.
Spectroscopy: (basics specially): Very very IMP topic. NMR, and C-NMR ranges from Morrison & Boyd or Pavia Mass -Basic concepts about various peaks M+1, molecular ion, base peak etc. (Silverstein) IR - Frequencies of various groups specially carbonyls. UV
Chromatography: Details of every chromatographic method.
Reaction kinetics, first second third and pseudo first order reactions, radio labeling for determination of mechanism.
Common condensation reactions like Aldol, Claisen Perkin, Dickmann, Darzen etc.
Other reactions like Cannizarro’s reaction, Prins reaction, especially reactions of carbonyl compounds.
References:
1. Jerry March
2. Morrison and Boyd (ESPECIALLY Peptide and Carbohydrate chemistry)
3. I. L. Finar Vol-I and Vol-II (Heterocyclic chemistry and organic synthesis)
4. Eliel
Natural Products:
In natural products more stress should be given on phytochemistry part rather than biological aspects.
Methods of extraction, isolation and characterization of natural products. Various separation techniques used for isolation of natural products.
Biosynthetic pathways.
Primary metabolites, their examples.
Secondary metabolites, various classes of secondary metabolites (e.g. Alkaloids, glycosides, tannins, lignans, saponins, lipids, flavonoids, coumarins, anthocyanidines etc.). Here most imp. Part is chemistry of these classes.
Important therapeutic classes: antidiabetics, hepatoprotectives, immmunomodulators, neutraceuticals, natural products for gynecological disorders, anti-cancer, anti-viral (mainly anti-HIV), adaptogens etc.
Dietary antioxidants, Marine natural products, Plant growth regulators.
Spectroscopy: Basic concepts of UV, NMR, IR and Mass spectroscopy. Give more stress on IR and NMR.
Stereochemistry: Basic concepts.
Fischer, sawhorse and newmon projection formulaes.
Biological sources of important classes of natural products. (Selected ones only)
Standardization of natural products.
What is difference between natural products and pharmacognosy?
References:
1. For various therapeutic classes: Trease and Evans
2. For spectroscopy: Silverstein, Pavia, Kemp.
3. For stereochemistry: I.L. Finar vol-II
Pharmacology and toxicology:
Pharmacokinetics, pharmacodynamics, pharmacological effect, desired, undesired, toxic, adverse effects.
Bioavailability, bioequivalence, various factors of ADME. (From Bramhankar)
Drug metabolism: various pathways and other details.
Drug interactions, agonist, antagonist, partial agonist, protein binding, drug distribution, distribution volume, excretion pathways etc.
Pharmacological screening: general principles, various screening models, screening methodologies (in vitro and in vivo tests).
Mechanism of drug action, drug-receptor interaction.
Various adrenergic, cholinergic and other receptors
Detailed study of CNS pharmacology
Study of basis of threshold areas of work in NIPER in pharmacology dept. mentioned in brochure.
Diseases: study of the pharmacology of the diseases and drugs used with mode of action especially of diabetes, malaria, leishmaniasis, TB, hypertension, myocardial ischemia, inflammation, and immunomodualtion.
Chemotherapy and pathophysiology- knowledge of antibiotics, their mode of action and the microorganisms responsible for various common diseases.
Bioassay methods, various requirements. Brief knowledge of the statistical tests.
References:
1. Rang and Dale (ALL CHEMOTHERAPY CLASSES OF DRUGS. IF YOU READ THE WHOLE BOOK, then nothing else is needed)
2. F. S. K. Barar
3. Wilson and Griswold (for Mechanism)
4. Kasture (for Bioassay and Screening)
Pharmaceutics and formulation (Pharmaceuticl Technology)
Drug delivery systems (DDS): NDDS models, osmotic pumps, various release patterns eg. Controlled release, delayed release. Sustained release etc., order of release. Oral controlled DDS, factors affecting controlled release.
Carriers in DDS: polymers and their classification, types, carbohydrates, surfactants, proteins, lipids, prodrugs etc.
Transdermal drug delivery systems (TDDS): principles, absorption enhancers, evaluation of TDDS.
Parenterals: requirements, advantages, disadvantages, release pattern, route of drug delivery.
Drug targeting: microspheres, nano particles, liposomes, monoclonal antibodies, etc.
Preformulation detailed.
Complexation, solubilization, polymerization, viscosity measurements.
Dosage form development- stages, implications of dosage form.
Additives of formulation, types, examples, advantages, disadvantages, drug excipient interaction, incompatibility, various types of incompatibilities.
Dosage forms: solid (tablets, capsules, pills etc), liquid (emulsion, suspension etc), sterile (injectables), aerosols. Principles, advantages, disadvantages and problems.
Coating - in detail.
Packaging: materials, labeling etc. Types of containers (e.g. Tamper-proof containers)
In process controls, Product specification, documentation.
Compartmental modeling. (From Bramhankar)
Bioavailability, bioequivalence studies. Methods of improvement of oral bioavailability.
Evaluation of formulation, principles and methods of release control in oral formulations.
References:
1. Lachmann (ALL new and old techniques in Pharmaceutical Industry)
2. Alfred Martin (ALL physical chemistry BASICS)
3. Remington’s Pharmaceutical Sciences
4. Notes of Gudsurkar Sir (Most important)
5. Banker series.
6. other: Bramhankar, , Liberman Series
Pharmaceutical analysis:
Stability testing of pharmaceuticals, various stability tests, kinetic studies, shelf life determination, thermal stability, formulation stability.
Various analytical techniques
Tests: physical and chemical tests, limit tests, microbiological tests, biological tests, disintegration and dissolution tests.
Spectroscopic methods; UV, NMR, IR, MS, FT-IR, FT-NMR, ATR (Attenuated Total Reflectance), FT-Raman- basics and applications.
Thermal techniques: DSC, DTA, TGA, etc.
Particle sizing: law of diffraction.
Electrophoresis: capillary electrophoresis.
Chromatography- detailed.
QA and QC: GLP, TQM, ISO system.
Preformulation, cyclodextrin inclusion compounds
Solubility: pH, pka, surfactant HLB values, Rheology.
Crystallinity, polymorphism, solvates and hydrates, crystal habits, porosity, surface area flow properties.
Dosage forms, Stages of dosage form development
Osmolality, osmolarity, osmotic pressure, conductivity, Preservatives, Media for bioassay.
References:
1. Willard
2. Silverstein (Mass Spectroscopy)
3. William Kemp (NMR)
4. Pavia (for spectroscopy)
5. Others like Alfred Martin, Chatwal (UV), Garry Christen (Chemical Methods)
Biotechnology:, Pharmaceutical technology biotechnology
Genetic Engg: Gene expression, mutation, replication, transcription, translation, recombination, bacteriophages.
Cloning: methods, isolation of nucleic acids, enzymes in cloning (restriction endonucleases, DNA ligase, DNA gyrase, polymerases etc...), functions of these enzymes, Pallindromes.
Fermentation: fermenters, fermentation process, its regulation, conditions, bioprocessors, various enzymes in fermentation technology. Fermentation of Antibiotics, vitamins, amino acids, hydroxy acids such as lactic acid etc. Chemical engg. aspects realated to fermentation
Gene therapy: methods and applications.
Monoclonal antibodies, insulin, interferons, enkephalins, angiotensin analogues and other peptides.
References:
1. Vyas and Dixit
2. IP Appendices
Practice of Pharmacy:
The best part for the preparation for this best reference for this would be Remington’s Pharmaceutical Sciences. This branch is quite new here, so till dates students of branch used to do case study of prescriptions in Fortis hospital, PGI Chandigarh and govt. college chd... This is much like pharmacology and drug-drug interactions and different interactions are emphasized. Diabetes, heart diseases are main area of study……….
Pharmacoinformatics:
Terminologies related with new emerging informatics e.g. proteomics, genomics, QSAR (2D, 3D, regression, correlation).
References:
Foye, Williams and Lemke, Medicinal chemistry, 5th/6th edition, chapter 1-6. (Computational drug design and molecular modeling).
Others:
Statistics, general mathematics and aptitude questions. Use MBA entrance test books like CET or CAT in MBA. Additionally some general awareness questions.
NIPER’s thrust areas are:
Microbial and viral diseases: Yeast, and fungi.
Parasitic and tropical diseases: Malaria, Leishmaniasis, amoebiasis, etc.
Metabolic Disorders: Diabetes
Strokes
Peptide and carbohydrate chemistry.
Genomics and proteomics: yeast and fungi
Hormonal disorders: TRH related diseases.

dear friend

Syllabus-

NIPER JEE is a very important entrance test for those who want to pursue postgraduate programmes in pharmacy - M.S (Pharm), M. Pharm, M. Tech (Pharm) and MBA (Pharm), offered by the institute.

The institute has not prescribed any particular syllabus for the preparation of this all-India level test. But questions in the competitive entrance test are generally asked from the curriculum of B. Pharma and M. Sc. (Relevant Field). The students can learn Biological Sciences, Organic Chemistry, Analytical Chemistry, Biochemistry / Biotechnology / Molecular Biology/ Microbiology, Pharmacology/ Toxicology/ Life, Sciences / Biochemistry / Medical Biotechnology.

Examination Pattern

The question paper consists of 200 multiple-choice type questions. The candidates
have to choose the right answer out of four given options. All the questions are
required to have answered by the candidates within two-hours duration, There
is a provision of negative marking the Joint Entrance Examination, that is, 25%
marks are deducted for each wrong answer.........

ok
all the best.

What is the course pattern for the NIPER exam and what are the reference book that are a must for this exam?

GK & English grammer r inclded in niper r not

What is NIPER entrance syllabus

from where can i get previous exanm papers of niper-jee for m.pharm?

though i cant give you sites,yes there are books of arihant publications.
seek them

dear friend,
solved papers and syllabus of NIPER entrance exam can be downloaded from the given link mentioned below:
www.successCDs.net

yhe question paper is of multiple choice type and their is negative marking also for each wrong answer 1/4 of the marks will be deduce.
all the best and don't go for wrong answer.

PLZ SEND ME SOLVED QUESTION OLD PAPERS OF NIPER.

plz give me solved question old paper of niper .

how to prepare for NIPER entrance exam???

dear friend,
the question paper will get from:http://niper.nic.in/
till now the syllabus is not published.you will get it latter in:www.niper.gov.in
best of luck

whether there is styfund

Originally Posted by Unregistered

plz give me solved question old paper of niper .

u will get papers of niper from career consultants nasik maharashtra phone 0253-2311422

is there negative marking in niper

Dear sir, plz.......send me last ten years solved papers of niper m.pharmacy entrance test. my email id:[email protected]

Originally Posted by Unregistered

is there negative marking in niper

Yes, negative marking is there in NIPER ( National Institute of Pharmaceutical Education and Research ) Exam...

PATTERN OF THE NIPER EXAM

-> Time - 2 hrs with 200 Multiple Choice questions.

-> Questions based on syllabus of B.Pharma and relevant field.

-> Negative marking of 25 % for every wrong answer.


POINTS TO NOTE :


-> As you have negative marking, its better you attempt the questions which you are sure of the answers.


-> Important Dates (tentative) to note for NIPER entrance exam.

-> Last date for form submission - April 4th week, 2011

-> Date of entrance exam - June 2nd week, 2011

i want 10 years Q.paper of niper so that i can get some idea

want 10 years Q.paper of niper so that i can get some idea

here are some of niper old papers..