Jaypee Institute of Information Technology conducts own entrance test for admission to M.Tech degree. Those with GATE qualification can also apply. The syllabus for the entrance test conducted for admission to M.Tech (Computational Biology) is based on topics of general sciences and biological sciences. Fifteen questions are asked from the section of general sciences and thirty five questions from biological sciences. Topics on Biostatistics, Physics, Chemistry, and Computer Science are asked from general sciences section where as questions on Biochemistry, Microbiology, Molecular Biology, Genetics, Bioinformatics, and Immunology are mainly asked for the section of biological sciences.

Syllabus for JIIT M.Tech (Computational Biology) Entrance Exam

Syllabus for General Sciences

Biostatistics

• Chi-square test
• Correlation and Regression
• F-statistics
• Mean, Median, and Mode
• Central tendency and dispersion
• Probability
• Skewness and Kurtosis
• Standard deviation
• Standard error of mean
• Testing of hypothesis
• T-statistics
• Z-statistics

Physics

• Applications of compression and expansion processes
• Concept of entropy
• Concept of free energy
• Excess properties of mixtures
• Laws of thermodynamics
• Solution thermodynamics

Chemistry

• Concept of pH and buffer
• Chemical bonding and hybridization
• Atomic and molecular structure
• Chemical reaction equilibrium
• Chemical reaction mechanism (SN1 and SN2)
• First & second order Chemical kinetics

Computer Science

• Logic Systems
• Binary, decimal, and hexa decimal number conversions
• Flow diagram
• Basics of databases and ER diagram
• Markup languages (HTML)

Syllabus for Biological Sciences

Biochemistry

• Amino acids
• Basic concepts of Enzymes
• Bio-molecular structure
• Catalytic and regulatory strategies
• Cell structure and function
• Fatty acids
• Metabolic disorders
• Metabolism and regulation of carbohydrate
• Nucleic acids

Microbiology

• Classification of microorganisms
• Anaerobic respiration
• Fermentation
• Growth and physiology
• Host-pathogen interactions
• Microbes in industry
• Microbial Metabolism
• Pathogenic microorganisms

Molecular Biology and Genetics

• Basic techniques of molecular Biology
• Cell division
• Central dogma of molecular biology
• DNA as genetic material
• DNA damage and repair
• DNA replication
• DNA super coiling
• DNA transcription
• Gene regulation
• Gene structure in prokaryotes and eukaryotes
• Genetic code and protein synthesis
• Genetic Disorders
• Mutations and their role in Evolution
• Physical and chemical properties of nucleic acids
• Population genetics
• Post-translational Modifications
• RNA processing
• Structure of DNA and RNA

Introduction to Bioinformatics

• Biological databases
• Sequence retrieval and analysis (NCBI & BLAST)
• Sequence alignment
• Construction of phylogenetic trees
• Gene predictions
• RNA and protein structure prediction

Immunology

• Antibody structure
• Antigen-antibody reaction
• Autoimmunity
• Basic immunology
• Complement system
• Hybridoma technology
• Hypersensitivity
• Immunity against infectious diseases
• Immunodeficiency diseases
• MHC and HLA
• T-cell receptors
• T-cells and B-cells
• Tissue and organ transplantation
• Types of immunity
• Vaccines

Exam preparation for these topics can be done using reference books and question papers of previous years. Web based study materials can also be used for study.