#1
27th October 2009, 07:46 PM
|
|||
|
|||
Syllabus of Niper JEE 2010
Sir/Mam could u forward the whole syllabus of Niper Jee 2010 along with old question papers with key points kindly send the reply, thanks sir.
|
#2
28th October 2009, 08:43 PM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
The detailed syllabus of NIPER JEE has not been made available however it has been declared that the questions will be from the syllabus of B. Pharma and MSc.(Relevant Field). Moreover the Entrance Test will be of 2 hours consisting of 200 Multiple Choice Questions. There will be negative marking of 25% for every incorrect answer.
Unfortunately the old question papers for NIPER JEE are not available on internet but you can enquire about them in the market. |
#3
15th December 2009, 09:41 AM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
this exam syllabus are the same what you study in b.pharma
|
#12
8th January 2010, 01:11 PM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
syllabus of niper jee is same as that of B.pharma...........for question papers you can go on its official sites
|
#14
12th January 2010, 02:34 PM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
the pattern of the exam is :-
The Entrance Test will be of 2 hours consisting of 200 Multiple Choice Questions. The questions will be from the syllabus of B. Pharma and MSc.(Relevant Field). There will be negative marking of 25% for every incorrect answer. syllabus is generally what you have done in graduation ....... best of luck |
#16
27th January 2010, 06:40 PM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
Quote:
|
#19
3rd February 2010, 11:37 PM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
hiiiiiiiiiiiiii.............u can get NIPER SYLLABUS from my blog
it is:http://eswathireddy.blogspot.com/ u also get details regarding the books to refer for niper ALL THE BEST. |
#21
15th March 2010, 01:45 AM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
dear friend
for the syllabus go to way2freshers.com/tag/niper-jee-2010-syllabus for model and previous questions visit www.pharmatutor.org/exam-alert/niper-jee-sample-papers.html www.winentrance.com/entrance_exam/niper_jee/ all the best |
#24
29th March 2010, 04:42 PM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
hi
you can download the syllabus from the following websites www.pharmatutor.org/exam-alert/niper-jee-sample-papers.html www.winentrance.com/entrance_exam/niper_jee/ http://blish.in.com/pharma-india/post/_niper_jee_2010_syllabus_-217566.html all the best |
#26
1st April 2010, 10:29 PM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
Quote:
i am a student of bpharm 3rd year i wish to go through the previous question papers of niper xam pls send it to my mail id |
#27
5th April 2010, 02:03 PM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
hi
you can get syllabus from http://www.pdfqueen.com/pdf/ni/niper--jee-syllabus-for-chemistry-m.sc-entrance/ http://www.winentrance.com/entrance_exam/niper_jee/ http://indiastudycircle.blogspot.com/2009/03/niper-jee-2009.html hi, aruna you can get papers from http://www.pharmatutor.org/exam-alert/niper-jee-sample-papers.html http://www.scribd.com/doc/16107209/NiperJee-Previous-Que http://indiastudycircle.blogspot.com/2010/02/niper-jee-2010.html http://www.winentrance.com/search/?q=NIPER+Exam+Papers best of luck |
#29
9th April 2010, 08:43 PM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
dear friends,
the syllabus for niper JEE 2010 is very easy. they can be downloaded from the website http://www.winentrance.com/entrance_exam/niper_jee/ http://indiastudycircle.blogspot.com/2009/03/niper-jee-2009.html http://blish.in.com/pharma-india/post/_niper_jee_2010_syllabus_-217566.html there are 200 questions.the negative marks for wrong is 1/4th of the the alloted marks to that questions. |
#30
10th April 2010, 05:59 AM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
dear friend
this exam consist of 200 objective question of duration 2 hour. syllabus is bacsically what you have studied in b. pharma for detailed syllabus please visit the link given below: www.pharmatutor.org/exam-alert/niper-jee-sample-papers.html www.winentrance.com/entrance_exam/niper_jee/ all the best |
#33
26th May 2010, 12:12 AM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
plz sir send me syllabus of admission in M-Pharm
sir,i have qualified the G-PAT exam & my rank is 4553 my email i.d. [email protected] my name is -amit khandelwal. |
#35
1st June 2010, 12:22 PM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
i want d syllabus of niper nd previous question paper.plz send me
my id is [email protected] |
#37
3rd June 2010, 09:39 PM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
hai sir, this is anand from warangal. sir i have qualified in Gpat2010. so i'm preparing fo niperjee 2010 for mpharmacy admission. so please send niperjee syllabus and old question papers for mpharmacy entance. so kindly send to my mail. hank you sir.
|
#38
4th June 2010, 12:40 PM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
want niper information.........and paper join my orkut [email protected] all india rank is 78.
|
#39
7th June 2010, 06:01 PM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
my scorecard for gpat2010 exam is massed byu post office,
can i submit the print of result published in site? pls reply imidietely on [email protected]. |
#44
17th June 2010, 01:39 AM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
dear friend........
You can get the previous exam papers from the famous bookshops....... |
#45
17th June 2010, 01:44 AM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
Quote:
NIPER EXAM PATTERN & SYLLABUS Entrance pattern: Well entrance consists of 200 questions in 2 hours. (Please check it in Brochure). Well questions will be very easy so no need to go in depth of the topic. Basic concepts based questions are asked. M. Pharma branches and M.B.A. has a common entrance paper. So read some general knowledge aspects also……………. This syllabus is just like GATE entrance but more specific in Basic Chemistry instead of medicinal chemistry. Specialization subjects: What to study….. Medicinal chemistry and Bulk Drugs (Pharmaceutical Technology) IUPAC nomenclature, R and S nomenclature, E and Z isomerism, atropiisomerism, Conformations Hybridization, aromaticity, Huckel’s rule reaction mechanisms- Electrophilic, Nucleophilic, SN1, SN2, SNi, Elimination E1 E2 etc. Ester hydrolysis, Aac1 Aac2……all eight mechanisms (Jerry march) Markovnikoves rule, Bredts rule, Stereoselectivity, stereospecificity, regioselectivity, chemoselectivity, chirality, stereochemistry, conformations, rearrangements, acids and bases. Imine-enamine Tautomerism, keto-enol tautomerism, pericyclic reactions, racemic mixture, resolution methods. Amino acids proteins, various methods for amino acid detection, Ninhydrin test, peptide sequencing, structures of amino acids, essential and nonessential amino acids, Introduction to thermal methods of analysis like, TGA, DSC, DTA etc. Carbohydrates classification, osazone test, mutarotation, etc, Various Heterocycles, Heterocycle synthesis, reactions. Introduction to Redox reactions. Spectroscopy: (basics specially): Very very IMP topic. NMR, and C-NMR ranges from Morrison & Boyd or Pavia Mass -Basic concepts about various peaks M+1, molecular ion, base peak etc. (Silverstein) IR - Frequencies of various groups specially carbonyls. UV Chromatography: Details of every chromatographic method. Reaction kinetics, first second third and pseudo first order reactions, radio labeling for determination of mechanism. Common condensation reactions like Aldol, Claisen Perkin, Dickmann, Darzen etc. Other reactions like Cannizarro’s reaction, Prins reaction, especially reactions of carbonyl compounds. References: 1. Jerry March 2. Morrison and Boyd (ESPECIALLY Peptide and Carbohydrate chemistry) 3. I. L. Finar Vol-I and Vol-II (Heterocyclic chemistry and organic synthesis) 4. Eliel Natural Products: In natural products more stress should be given on phytochemistry part rather than biological aspects. Methods of extraction, isolation and characterization of natural products. Various separation techniques used for isolation of natural products. Biosynthetic pathways. Primary metabolites, their examples. Secondary metabolites, various classes of secondary metabolites (e.g. Alkaloids, glycosides, tannins, lignans, saponins, lipids, flavonoids, coumarins, anthocyanidines etc.). Here most imp. Part is chemistry of these classes. Important therapeutic classes: antidiabetics, hepatoprotectives, immmunomodulators, neutraceuticals, natural products for gynecological disorders, anti-cancer, anti-viral (mainly anti-HIV), adaptogens etc. Dietary antioxidants, Marine natural products, Plant growth regulators. Spectroscopy: Basic concepts of UV, NMR, IR and Mass spectroscopy. Give more stress on IR and NMR. Stereochemistry: Basic concepts. Fischer, sawhorse and newmon projection formulaes. Biological sources of important classes of natural products. (Selected ones only) Standardization of natural products. What is difference between natural products and pharmacognosy? References: 1. For various therapeutic classes: Trease and Evans 2. For spectroscopy: Silverstein, Pavia, Kemp. 3. For stereochemistry: I.L. Finar vol-II Pharmacology and toxicology: Pharmacokinetics, pharmacodynamics, pharmacological effect, desired, undesired, toxic, adverse effects. Bioavailability, bioequivalence, various factors of ADME. (From Bramhankar) Drug metabolism: various pathways and other details. Drug interactions, agonist, antagonist, partial agonist, protein binding, drug distribution, distribution volume, excretion pathways etc. Pharmacological screening: general principles, various screening models, screening methodologies (in vitro and in vivo tests). Mechanism of drug action, drug-receptor interaction. Various adrenergic, cholinergic and other receptors Detailed study of CNS pharmacology Study of basis of threshold areas of work in NIPER in pharmacology dept. mentioned in brochure. Diseases: study of the pharmacology of the diseases and drugs used with mode of action especially of diabetes, malaria, leishmaniasis, TB, hypertension, myocardial ischemia, inflammation, and immunomodualtion. Chemotherapy and pathophysiology- knowledge of antibiotics, their mode of action and the microorganisms responsible for various common diseases. Bioassay methods, various requirements. Brief knowledge of the statistical tests. References: 1. Rang and Dale (ALL CHEMOTHERAPY CLASSES OF DRUGS. IF YOU READ THE WHOLE BOOK, then nothing else is needed) 2. F. S. K. Barar 3. Wilson and Griswold (for Mechanism) 4. Kasture (for Bioassay and Screening) Pharmaceutics and formulation (Pharmaceuticl Technology) Drug delivery systems (DDS): NDDS models, osmotic pumps, various release patterns eg. Controlled release, delayed release. Sustained release etc., order of release. Oral controlled DDS, factors affecting controlled release. Carriers in DDS: polymers and their classification, types, carbohydrates, surfactants, proteins, lipids, prodrugs etc. Transdermal drug delivery systems (TDDS): principles, absorption enhancers, evaluation of TDDS. Parenterals: requirements, advantages, disadvantages, release pattern, route of drug delivery. Drug targeting: microspheres, nano particles, liposomes, monoclonal antibodies, etc. Preformulation detailed. Complexation, solubilization, polymerization, viscosity measurements. Dosage form development- stages, implications of dosage form. Additives of formulation, types, examples, advantages, disadvantages, drug excipient interaction, incompatibility, various types of incompatibilities. Dosage forms: solid (tablets, capsules, pills etc), liquid (emulsion, suspension etc), sterile (injectables), aerosols. Principles, advantages, disadvantages and problems. Coating - in detail. Packaging: materials, labeling etc. Types of containers (e.g. Tamper-proof containers) In process controls, Product specification, documentation. Compartmental modeling. (From Bramhankar) Bioavailability, bioequivalence studies. Methods of improvement of oral bioavailability. Evaluation of formulation, principles and methods of release control in oral formulations. References: 1. Lachmann (ALL new and old techniques in Pharmaceutical Industry) 2. Alfred Martin (ALL physical chemistry BASICS) 3. Remington’s Pharmaceutical Sciences 4. Notes of Gudsurkar Sir (Most important) 5. Banker series. 6. other: Bramhankar, , Liberman Series Pharmaceutical analysis: Stability testing of pharmaceuticals, various stability tests, kinetic studies, shelf life determination, thermal stability, formulation stability. Various analytical techniques Tests: physical and chemical tests, limit tests, microbiological tests, biological tests, disintegration and dissolution tests. Spectroscopic methods; UV, NMR, IR, MS, FT-IR, FT-NMR, ATR (Attenuated Total Reflectance), FT-Raman- basics and applications. Thermal techniques: DSC, DTA, TGA, etc. Particle sizing: law of diffraction. Electrophoresis: capillary electrophoresis. Chromatography- detailed. QA and QC: GLP, TQM, ISO system. Preformulation, cyclodextrin inclusion compounds Solubility: pH, pka, surfactant HLB values, Rheology. Crystallinity, polymorphism, solvates and hydrates, crystal habits, porosity, surface area flow properties. Dosage forms, Stages of dosage form development Osmolality, osmolarity, osmotic pressure, conductivity, Preservatives, Media for bioassay. References: 1. Willard 2. Silverstein (Mass Spectroscopy) 3. William Kemp (NMR) 4. Pavia (for spectroscopy) 5. Others like Alfred Martin, Chatwal (UV), Garry Christen (Chemical Methods) Biotechnology:Pharmaceutical technology biotechnology Genetic Engg: Gene expression, mutation, replication, transcription, translation, recombination, bacteriophages. Cloning: methods, isolation of nucleic acids, enzymes in cloning (restriction endonucleases, DNA ligase, DNA gyrase, polymerases etc...), functions of these enzymes, Pallindromes. Fermentation: fermenters, fermentation process, its regulation, conditions, bioprocessors, various enzymes in fermentation technology. Fermentation of Antibiotics, vitamins, amino acids, hydroxy acids such as lactic acid etc. Chemical engg. aspects realated to fermentation Gene therapy: methods and applications. Monoclonal antibodies, insulin, interferons, enkephalins, angiotensin analogues and other peptides. References: 1. Vyas and Dixit 2. IP Appendices Practice of Pharmacy: The best part for the preparation for this best reference for this would be Remington’s Pharmaceutical Sciences. This branch is quite new here, so till dates students of branch used to do case study of prescriptions in Fortis hospital, PGI Chandigarh and govt. college chd... This is much like pharmacology and drug-drug interactions and different interactions are emphasized. Diabetes, heart diseases are main area of study………. Pharmacoinformatics: Terminologies related with new emerging informatics e.g. proteomics, genomics, QSAR (2D, 3D, regression, correlation). References: Foye, Williams and Lemke, Medicinal chemistry, 5th/6th edition, chapter 1-6. (Computational drug design and molecular modeling). Others: Statistics, general mathematics and aptitude questions. Use MBA entrance test books like CET or CAT in MBA. Additionally some general awareness questions. NIPER’s thrust areas are: Microbial and viral diseases: Yeast, and fungi. Parasitic and tropical diseases: Malaria, Leishmaniasis, amoebiasis, etc. Metabolic Disorders: Diabetes Strokes Peptide and carbohydrate chemistry. Genomics and proteomics: yeast and fungi Hormonal disorders: TRH related diseases. |
#46
17th June 2010, 01:45 AM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
Quote:
NIPER EXAM PATTERN & SYLLABUS Entrance pattern: Well entrance consists of 200 questions in 2 hours. (Please check it in Brochure). Well questions will be very easy so no need to go in depth of the topic. Basic concepts based questions are asked. M. Pharma branches and M.B.A. has a common entrance paper. So read some general knowledge aspects also……………. This syllabus is just like GATE entrance but more specific in Basic Chemistry instead of medicinal chemistry. Specialization subjects: What to study….. Medicinal chemistry and Bulk Drugs (Pharmaceutical Technology) IUPAC nomenclature, R and S nomenclature, E and Z isomerism, atropiisomerism, Conformations Hybridization, aromaticity, Huckel’s rule reaction mechanisms- Electrophilic, Nucleophilic, SN1, SN2, SNi, Elimination E1 E2 etc. Ester hydrolysis, Aac1 Aac2……all eight mechanisms (Jerry march) Markovnikoves rule, Bredts rule, Stereoselectivity, stereospecificity, regioselectivity, chemoselectivity, chirality, stereochemistry, conformations, rearrangements, acids and bases. Imine-enamine Tautomerism, keto-enol tautomerism, pericyclic reactions, racemic mixture, resolution methods. Amino acids proteins, various methods for amino acid detection, Ninhydrin test, peptide sequencing, structures of amino acids, essential and nonessential amino acids, Introduction to thermal methods of analysis like, TGA, DSC, DTA etc. Carbohydrates classification, osazone test, mutarotation, etc, Various Heterocycles, Heterocycle synthesis, reactions. Introduction to Redox reactions. Spectroscopy: (basics specially): Very very IMP topic. NMR, and C-NMR ranges from Morrison & Boyd or Pavia Mass -Basic concepts about various peaks M+1, molecular ion, base peak etc. (Silverstein) IR - Frequencies of various groups specially carbonyls. UV Chromatography: Details of every chromatographic method. Reaction kinetics, first second third and pseudo first order reactions, radio labeling for determination of mechanism. Common condensation reactions like Aldol, Claisen Perkin, Dickmann, Darzen etc. Other reactions like Cannizarro’s reaction, Prins reaction, especially reactions of carbonyl compounds. References: 1. Jerry March 2. Morrison and Boyd (ESPECIALLY Peptide and Carbohydrate chemistry) 3. I. L. Finar Vol-I and Vol-II (Heterocyclic chemistry and organic synthesis) 4. Eliel Natural Products: In natural products more stress should be given on phytochemistry part rather than biological aspects. Methods of extraction, isolation and characterization of natural products. Various separation techniques used for isolation of natural products. Biosynthetic pathways. Primary metabolites, their examples. Secondary metabolites, various classes of secondary metabolites (e.g. Alkaloids, glycosides, tannins, lignans, saponins, lipids, flavonoids, coumarins, anthocyanidines etc.). Here most imp. Part is chemistry of these classes. Important therapeutic classes: antidiabetics, hepatoprotectives, immmunomodulators, neutraceuticals, natural products for gynecological disorders, anti-cancer, anti-viral (mainly anti-HIV), adaptogens etc. Dietary antioxidants, Marine natural products, Plant growth regulators. Spectroscopy: Basic concepts of UV, NMR, IR and Mass spectroscopy. Give more stress on IR and NMR. Stereochemistry: Basic concepts. Fischer, sawhorse and newmon projection formulaes. Biological sources of important classes of natural products. (Selected ones only) Standardization of natural products. What is difference between natural products and pharmacognosy? References: 1. For various therapeutic classes: Trease and Evans 2. For spectroscopy: Silverstein, Pavia, Kemp. 3. For stereochemistry: I.L. Finar vol-II Pharmacology and toxicology: Pharmacokinetics, pharmacodynamics, pharmacological effect, desired, undesired, toxic, adverse effects. Bioavailability, bioequivalence, various factors of ADME. (From Bramhankar) Drug metabolism: various pathways and other details. Drug interactions, agonist, antagonist, partial agonist, protein binding, drug distribution, distribution volume, excretion pathways etc. Pharmacological screening: general principles, various screening models, screening methodologies (in vitro and in vivo tests). Mechanism of drug action, drug-receptor interaction. Various adrenergic, cholinergic and other receptors Detailed study of CNS pharmacology Study of basis of threshold areas of work in NIPER in pharmacology dept. mentioned in brochure. Diseases: study of the pharmacology of the diseases and drugs used with mode of action especially of diabetes, malaria, leishmaniasis, TB, hypertension, myocardial ischemia, inflammation, and immunomodualtion. Chemotherapy and pathophysiology- knowledge of antibiotics, their mode of action and the microorganisms responsible for various common diseases. Bioassay methods, various requirements. Brief knowledge of the statistical tests. References: 1. Rang and Dale (ALL CHEMOTHERAPY CLASSES OF DRUGS. IF YOU READ THE WHOLE BOOK, then nothing else is needed) 2. F. S. K. Barar 3. Wilson and Griswold (for Mechanism) 4. Kasture (for Bioassay and Screening) Pharmaceutics and formulation (Pharmaceuticl Technology) Drug delivery systems (DDS): NDDS models, osmotic pumps, various release patterns eg. Controlled release, delayed release. Sustained release etc., order of release. Oral controlled DDS, factors affecting controlled release. Carriers in DDS: polymers and their classification, types, carbohydrates, surfactants, proteins, lipids, prodrugs etc. Transdermal drug delivery systems (TDDS): principles, absorption enhancers, evaluation of TDDS. Parenterals: requirements, advantages, disadvantages, release pattern, route of drug delivery. Drug targeting: microspheres, nano particles, liposomes, monoclonal antibodies, etc. Preformulation detailed. Complexation, solubilization, polymerization, viscosity measurements. Dosage form development- stages, implications of dosage form. Additives of formulation, types, examples, advantages, disadvantages, drug excipient interaction, incompatibility, various types of incompatibilities. Dosage forms: solid (tablets, capsules, pills etc), liquid (emulsion, suspension etc), sterile (injectables), aerosols. Principles, advantages, disadvantages and problems. Coating - in detail. Packaging: materials, labeling etc. Types of containers (e.g. Tamper-proof containers) In process controls, Product specification, documentation. Compartmental modeling. (From Bramhankar) Bioavailability, bioequivalence studies. Methods of improvement of oral bioavailability. Evaluation of formulation, principles and methods of release control in oral formulations. References: 1. Lachmann (ALL new and old techniques in Pharmaceutical Industry) 2. Alfred Martin (ALL physical chemistry BASICS) 3. Remington’s Pharmaceutical Sciences 4. Notes of Gudsurkar Sir (Most important) 5. Banker series. 6. other: Bramhankar, , Liberman Series Pharmaceutical analysis: Stability testing of pharmaceuticals, various stability tests, kinetic studies, shelf life determination, thermal stability, formulation stability. Various analytical techniques Tests: physical and chemical tests, limit tests, microbiological tests, biological tests, disintegration and dissolution tests. Spectroscopic methods; UV, NMR, IR, MS, FT-IR, FT-NMR, ATR (Attenuated Total Reflectance), FT-Raman- basics and applications. Thermal techniques: DSC, DTA, TGA, etc. Particle sizing: law of diffraction. Electrophoresis: capillary electrophoresis. Chromatography- detailed. QA and QC: GLP, TQM, ISO system. Preformulation, cyclodextrin inclusion compounds Solubility: pH, pka, surfactant HLB values, Rheology. Crystallinity, polymorphism, solvates and hydrates, crystal habits, porosity, surface area flow properties. Dosage forms, Stages of dosage form development Osmolality, osmolarity, osmotic pressure, conductivity, Preservatives, Media for bioassay. References: 1. Willard 2. Silverstein (Mass Spectroscopy) 3. William Kemp (NMR) 4. Pavia (for spectroscopy) 5. Others like Alfred Martin, Chatwal (UV), Garry Christen (Chemical Methods) Biotechnology:Pharmaceutical technology biotechnology Genetic Engg: Gene expression, mutation, replication, transcription, translation, recombination, bacteriophages. Cloning: methods, isolation of nucleic acids, enzymes in cloning (restriction endonucleases, DNA ligase, DNA gyrase, polymerases etc...), functions of these enzymes, Pallindromes. Fermentation: fermenters, fermentation process, its regulation, conditions, bioprocessors, various enzymes in fermentation technology. Fermentation of Antibiotics, vitamins, amino acids, hydroxy acids such as lactic acid etc. Chemical engg. aspects realated to fermentation Gene therapy: methods and applications. Monoclonal antibodies, insulin, interferons, enkephalins, angiotensin analogues and other peptides. References: 1. Vyas and Dixit 2. IP Appendices Practice of Pharmacy: The best part for the preparation for this best reference for this would be Remington’s Pharmaceutical Sciences. This branch is quite new here, so till dates students of branch used to do case study of prescriptions in Fortis hospital, PGI Chandigarh and govt. college chd... This is much like pharmacology and drug-drug interactions and different interactions are emphasized. Diabetes, heart diseases are main area of study………. Pharmacoinformatics: Terminologies related with new emerging informatics e.g. proteomics, genomics, QSAR (2D, 3D, regression, correlation). References: Foye, Williams and Lemke, Medicinal chemistry, 5th/6th edition, chapter 1-6. (Computational drug design and molecular modeling). Others: Statistics, general mathematics and aptitude questions. Use MBA entrance test books like CET or CAT in MBA. Additionally some general awareness questions. NIPER’s thrust areas are: Microbial and viral diseases: Yeast, and fungi. Parasitic and tropical diseases: Malaria, Leishmaniasis, amoebiasis, etc. Metabolic Disorders: Diabetes Strokes Peptide and carbohydrate chemistry. Genomics and proteomics: yeast and fungi Hormonal disorders: TRH related diseases. |
#47
17th June 2010, 01:46 AM
|
|||
|
|||
Re: Syllabus of Niper JEE 2010
Quote:
NIPER EXAM PATTERN & SYLLABUS Entrance pattern: Well entrance consists of 200 questions in 2 hours. (Please check it in Brochure). Well questions will be very easy so no need to go in depth of the topic. Basic concepts based questions are asked. M. Pharma branches and M.B.A. has a common entrance paper. So read some general knowledge aspects also……………. This syllabus is just like GATE entrance but more specific in Basic Chemistry instead of medicinal chemistry. Specialization subjects: What to study….. Medicinal chemistry and Bulk Drugs (Pharmaceutical Technology) IUPAC nomenclature, R and S nomenclature, E and Z isomerism, atropiisomerism, Conformations Hybridization, aromaticity, Huckel’s rule reaction mechanisms- Electrophilic, Nucleophilic, SN1, SN2, SNi, Elimination E1 E2 etc. Ester hydrolysis, Aac1 Aac2……all eight mechanisms (Jerry march) Markovnikoves rule, Bredts rule, Stereoselectivity, stereospecificity, regioselectivity, chemoselectivity, chirality, stereochemistry, conformations, rearrangements, acids and bases. Imine-enamine Tautomerism, keto-enol tautomerism, pericyclic reactions, racemic mixture, resolution methods. Amino acids proteins, various methods for amino acid detection, Ninhydrin test, peptide sequencing, structures of amino acids, essential and nonessential amino acids, Introduction to thermal methods of analysis like, TGA, DSC, DTA etc. Carbohydrates classification, osazone test, mutarotation, etc, Various Heterocycles, Heterocycle synthesis, reactions. Introduction to Redox reactions. Spectroscopy: (basics specially): Very very IMP topic. NMR, and C-NMR ranges from Morrison & Boyd or Pavia Mass -Basic concepts about various peaks M+1, molecular ion, base peak etc. (Silverstein) IR - Frequencies of various groups specially carbonyls. UV Chromatography: Details of every chromatographic method. Reaction kinetics, first second third and pseudo first order reactions, radio labeling for determination of mechanism. Common condensation reactions like Aldol, Claisen Perkin, Dickmann, Darzen etc. Other reactions like Cannizarro’s reaction, Prins reaction, especially reactions of carbonyl compounds. References: 1. Jerry March 2. Morrison and Boyd (ESPECIALLY Peptide and Carbohydrate chemistry) 3. I. L. Finar Vol-I and Vol-II (Heterocyclic chemistry and organic synthesis) 4. Eliel Natural Products: In natural products more stress should be given on phytochemistry part rather than biological aspects. Methods of extraction, isolation and characterization of natural products. Various separation techniques used for isolation of natural products. Biosynthetic pathways. Primary metabolites, their examples. Secondary metabolites, various classes of secondary metabolites (e.g. Alkaloids, glycosides, tannins, lignans, saponins, lipids, flavonoids, coumarins, anthocyanidines etc.). Here most imp. Part is chemistry of these classes. Important therapeutic classes: antidiabetics, hepatoprotectives, immmunomodulators, neutraceuticals, natural products for gynecological disorders, anti-cancer, anti-viral (mainly anti-HIV), adaptogens etc. Dietary antioxidants, Marine natural products, Plant growth regulators. Spectroscopy: Basic concepts of UV, NMR, IR and Mass spectroscopy. Give more stress on IR and NMR. Stereochemistry: Basic concepts. Fischer, sawhorse and newmon projection formulaes. Biological sources of important classes of natural products. (Selected ones only) Standardization of natural products. What is difference between natural products and pharmacognosy? References: 1. For various therapeutic classes: Trease and Evans 2. For spectroscopy: Silverstein, Pavia, Kemp. 3. For stereochemistry: I.L. Finar vol-II Pharmacology and toxicology: Pharmacokinetics, pharmacodynamics, pharmacological effect, desired, undesired, toxic, adverse effects. Bioavailability, bioequivalence, various factors of ADME. (From Bramhankar) Drug metabolism: various pathways and other details. Drug interactions, agonist, antagonist, partial agonist, protein binding, drug distribution, distribution volume, excretion pathways etc. Pharmacological screening: general principles, various screening models, screening methodologies (in vitro and in vivo tests). Mechanism of drug action, drug-receptor interaction. Various adrenergic, cholinergic and other receptors Detailed study of CNS pharmacology Study of basis of threshold areas of work in NIPER in pharmacology dept. mentioned in brochure. Diseases: study of the pharmacology of the diseases and drugs used with mode of action especially of diabetes, malaria, leishmaniasis, TB, hypertension, myocardial ischemia, inflammation, and immunomodualtion. Chemotherapy and pathophysiology- knowledge of antibiotics, their mode of action and the microorganisms responsible for various common diseases. Bioassay methods, various requirements. Brief knowledge of the statistical tests. References: 1. Rang and Dale (ALL CHEMOTHERAPY CLASSES OF DRUGS. IF YOU READ THE WHOLE BOOK, then nothing else is needed) 2. F. S. K. Barar 3. Wilson and Griswold (for Mechanism) 4. Kasture (for Bioassay and Screening) Pharmaceutics and formulation (Pharmaceuticl Technology) Drug delivery systems (DDS): NDDS models, osmotic pumps, various release patterns eg. Controlled release, delayed release. Sustained release etc., order of release. Oral controlled DDS, factors affecting controlled release. Carriers in DDS: polymers and their classification, types, carbohydrates, surfactants, proteins, lipids, prodrugs etc. Transdermal drug delivery systems (TDDS): principles, absorption enhancers, evaluation of TDDS. Parenterals: requirements, advantages, disadvantages, release pattern, route of drug delivery. Drug targeting: microspheres, nano particles, liposomes, monoclonal antibodies, etc. Preformulation detailed. Complexation, solubilization, polymerization, viscosity measurements. Dosage form development- stages, implications of dosage form. Additives of formulation, types, examples, advantages, disadvantages, drug excipient interaction, incompatibility, various types of incompatibilities. Dosage forms: solid (tablets, capsules, pills etc), liquid (emulsion, suspension etc), sterile (injectables), aerosols. Principles, advantages, disadvantages and problems. Coating - in detail. Packaging: materials, labeling etc. Types of containers (e.g. Tamper-proof containers) In process controls, Product specification, documentation. Compartmental modeling. (From Bramhankar) Bioavailability, bioequivalence studies. Methods of improvement of oral bioavailability. Evaluation of formulation, principles and methods of release control in oral formulations. References: 1. Lachmann (ALL new and old techniques in Pharmaceutical Industry) 2. Alfred Martin (ALL physical chemistry BASICS) 3. Remington’s Pharmaceutical Sciences 4. Notes of Gudsurkar Sir (Most important) 5. Banker series. 6. other: Bramhankar, , Liberman Series Pharmaceutical analysis: Stability testing of pharmaceuticals, various stability tests, kinetic studies, shelf life determination, thermal stability, formulation stability. Various analytical techniques Tests: physical and chemical tests, limit tests, microbiological tests, biological tests, disintegration and dissolution tests. Spectroscopic methods; UV, NMR, IR, MS, FT-IR, FT-NMR, ATR (Attenuated Total Reflectance), FT-Raman- basics and applications. Thermal techniques: DSC, DTA, TGA, etc. Particle sizing: law of diffraction. Electrophoresis: capillary electrophoresis. Chromatography- detailed. QA and QC: GLP, TQM, ISO system. Preformulation, cyclodextrin inclusion compounds Solubility: pH, pka, surfactant HLB values, Rheology. Crystallinity, polymorphism, solvates and hydrates, crystal habits, porosity, surface area flow properties. Dosage forms, Stages of dosage form development Osmolality, osmolarity, osmotic pressure, conductivity, Preservatives, Media for bioassay. References: 1. Willard 2. Silverstein (Mass Spectroscopy) 3. William Kemp (NMR) 4. Pavia (for spectroscopy) 5. Others like Alfred Martin, Chatwal (UV), Garry Christen (Chemical Methods) Biotechnology:Pharmaceutical technology biotechnology Genetic Engg: Gene expression, mutation, replication, transcription, translation, recombination, bacteriophages. Cloning: methods, isolation of nucleic acids, enzymes in cloning (restriction endonucleases, DNA ligase, DNA gyrase, polymerases etc...), functions of these enzymes, Pallindromes. Fermentation: fermenters, fermentation process, its regulation, conditions, bioprocessors, various enzymes in fermentation technology. Fermentation of Antibiotics, vitamins, amino acids, hydroxy acids such as lactic acid etc. Chemical engg. aspects realated to fermentation Gene therapy: methods and applications. Monoclonal antibodies, insulin, interferons, enkephalins, angiotensin analogues and other peptides. References: 1. Vyas and Dixit 2. IP Appendices Practice of Pharmacy: The best part for the preparation for this best reference for this would be Remington’s Pharmaceutical Sciences. This branch is quite new here, so till dates students of branch used to do case study of prescriptions in Fortis hospital, PGI Chandigarh and govt. college chd... This is much like pharmacology and drug-drug interactions and different interactions are emphasized. Diabetes, heart diseases are main area of study………. Pharmacoinformatics: Terminologies related with new emerging informatics e.g. proteomics, genomics, QSAR (2D, 3D, regression, correlation). References: Foye, Williams and Lemke, Medicinal chemistry, 5th/6th edition, chapter 1-6. (Computational drug design and molecular modeling). Others: Statistics, general mathematics and aptitude questions. Use MBA entrance test books like CET or CAT in MBA. Additionally some general awareness questions. NIPER’s thrust areas are: Microbial and viral diseases: Yeast, and fungi. Parasitic and tropical diseases: Malaria, Leishmaniasis, amoebiasis, etc. Metabolic Disorders: Diabetes Strokes Peptide and carbohydrate chemistry. Genomics and proteomics: yeast and fungi Hormonal disorders: TRH related diseases. |
Related Topics: |
||
Thread | Replies | Last Post |
Where in Guwahati will I get the form for M.Pharma admission in NIPER Guwahati? What is the syllabus of examination? | 2 | 2nd July 2012 05:31 PM |
I want to know the syllabus of NIPER 2010 | 5 | 12th May 2010 08:30 PM |
Syllabus for niper 2010? I am doing B.Pharm | 9 | 12th May 2010 08:29 PM |
|