NIPER JEE Exam is conducted by the National Institute of Pharmaceutical Education and Research (NIPER). National Institute of Pharmaceutical Education and Research (NIPER) is the well-known pharmacy institute of the country offering numerous post graduate programs in pharmacy. The institute conducts National Institute of Pharmaceutical Education and Research Joint Entrance Exam (NIPER JEE) for the admission for candidates.

Structure of NIPER JEE Exam

NIPER JEE exam consists of 200 questions and the maximum time allowed is 2 hours. Questions will be mainly from the core topics of M.Pharm. The syllabus is similar to that of GATE entrance exam but the difference is that, here more importance is given for Chemistry related subjects.

Syllabus for NIPER JEE Exam

Chemistry

• Amino acids proteins
• Aromaticity
• Carbohydrates classification
• Chromatography
• Common condensation reactions like Aldol, Claisen Perkin, Dickmann, Darzen
• E and Z isomerism
• Huckel’s rule reaction mechanisms-Ester hydrolysis
• Hybridization
• Imine-enamine
• Introduction to Redox reactions
• Introduction to thermal methods of analysis
• IUPAC nomenclature
• Keto-enol tautomerism
• Medicinal chemistry and Bulk Drugs
• Mutarotation
• Osazone test
• Pericyclic reactions
• Reactions like Cannizarro’s reaction
• R and S nomenclature
• Racemic mixture
• Reaction kinetics, first second third and pseudo first order reactions, radio labeling for determination of mechanism.
• Resolution methods
• Spectroscopy
• Tautomerism
• Various Heterocycles, Heterocycle synthesis, reactions

Natural Products

• Phytochemistry
• Methods of extraction, isolation and characterization of natural products
• Biosynthetic pathways
• Primary metabolites
• Secondary metabolites
• Important therapeutic classes
• Dietary antioxidants
• Marine natural products
• Plant growth regulators
• Spectroscopy

Stereochemistry

• Fischer, sawhorse and newmon projection formulaes
• Biological sources of important classes of natural products
• Standardization of natural products
• Pharmacology and toxicology
• Pharmacokinetics
• Pharmacodynamics
• Pharmacological effect, desired, undesired, toxic, adverse effects
• Bioavailability, bioequivalence, various factors of ADME
• Drug metabolism
• Drug interactions, agonist, antagonist, protein binding, drug distribution, distribution volume, excretion pathways
• Pharmacological screening
• Mechanism of drug action
• Drug-receptor interaction
• Various adrenergic, cholinergic and other receptors
• Detailed study of CNS pharmacology
• Diseases
• Chemotherapy and pathophysiology
• Bioassay methods
• Pharmaceutics and formulation (Pharmaceutical Technology)
• Drug delivery systems (DDS)
• Carriers in DDS
• Transdermal drug delivery systems (TDDS)
• Parenterals
• Drug targeting
• Complexation
• Solubilization
• Polymerization
• Viscosity measurements
• Dosage form development- stages, implications of dosage form
• Additives of formulation, types, examples, advantages, disadvantages, drug excipient interaction, incompatibility, various types of incompatibilities
• Dosage forms
• Packaging
• Compartmental modeling
• Bioavailability, bioequivalence studies
• Evaluation of formulation, principles and methods of release control in oral formulations

Pharmaceutical analysis

• Stability testing of pharmaceuticals, various stability tests, kinetic studies, shelf life determination, thermal stability, formulation stability
• Various analytical techniques
• Tests: physical and chemical tests, limit tests, microbiological tests, biological tests, disintegration and dissolution tests.
• Spectroscopic methods
• Particle sizing
• Electrophoresis
• Chromatography- detailed
• QA and QC: GLP, TQM, ISO system
• Preformulation, cyclodextrin inclusion compounds
• Solubility
• Crystallinity, polymorphism, solvates and hydrates, crystal habits, porosity, surface area flow properties.
• Dosage forms, Stages of dosage form development
• Osmolality, osmolarity, osmotic pressure, conductivity, Preservatives, Media for bioassay

Biotechnology

• Pharmaceutical technology
• Genetic Engineering

Gene expression

• Mutation
• Replication
• Transcription, translation
• Recombination, bacteriophages

Cloning

• Fermentation
• Methods, isolation of nucleic acids, enzymes in cloning

Preparing for NIPER JEE Exam

Candidates who wish to write NIPER JEE Exam must concentrate more on pharmacy papers. It will be more beneficial if they are referring previous year question papers. Candidates should try to collect maximum study materials. Studying in a systemic order helps them in efficiently utilizing the allowed time properly and it thereby increases their confidence level. Syllabus is very wide and so dividing into smaller units while preparing for the exam will be more effective as it reduces the study load.